临床荟萃 ›› 2025, Vol. 40 ›› Issue (5): 394-399.doi: 10.3969/j.issn.1004-583X.2025.05.002

• 循证研究 • 上一篇    下一篇

经导管主动脉瓣置换术治疗严重主动脉狭窄中自膨胀瓣膜与球囊扩张瓣膜的术后并发症的meta分析

温灿, 彭勇, 刘丹, 范剑峰()   

  1. 南昌市第一医院 心内二科,江西 南昌 330000
  • 收稿日期:2025-02-14 出版日期:2025-05-20 发布日期:2025-05-23
  • 通讯作者: 范剑峰 E-mail:390696271@qq.com
  • 基金资助:
    南昌市新技术新业务引进项目——经导管主动脉瓣置换术治疗重度主动脉瓣狭窄的临床应用(洪2023号)

Meta-analysis of postoperative complications of self-expanding valve and balloon-expanding valve in transcatheter aortic valve replacement for severe aortic stenosis

Wen Can, Peng Yong, Liu Dan, Fan Jianfeng()   

  1. Second Department of Cardiology, the First Hospital of Nanchang, Nanchang 330000, China
  • Received:2025-02-14 Online:2025-05-20 Published:2025-05-23
  • Contact: Fan Jianfeng E-mail:390696271@qq.com

摘要:

目的 探讨经导管主动脉瓣置换术中自膨胀瓣膜(SEV)与球囊扩张膜(BEV)的术后并发症差异。方法 检索PubMed、Cochrance等外文数据库,中国知网、万方、维普等中文数据库,通过提取文献中数据,对比SEV与BEV的术后并发症优劣势。结果 最终纳入9篇文献5 939患者。SEV在术后死亡率方面优于BEV(RR:1.34, 95%CI:1.08,1.66)。2组术后卒中发生率、术后起博器植入率、中重度瓣周漏发生率差异均无统计学意义(P>0.05)。结论 SEV在全因死亡率方面优于BEV,而卒中、中重度瓣周漏、起搏器植入率方面等术后并发症均无明显差异。

关键词: 经导管主动脉瓣置换, 自膨胀瓣膜, 球囊扩张瓣膜, 术后并发症

Abstract:

Objective To compare the postoperative complications of self-expanding valve (SEV) versus balloon-expanding valve (BEV) in transcatheter aortic valve replacement. Methods Articles reporting the advantages and disadvantages concerning the postoperative complications of SEV versus BEV in TAVR were searched in the English-language databases, such as PubMed and Cochrance, and Chinese-language databases, such as China National Knowledge Infrastructure (CNKI), Wanfang and VIP. Results A total of 9 articles, involving 5, 939 patients were included. There was a significant difference in the postoperative all-cause mortality between the SEV and BEV groups (risk ratio [RR]: 1.34, 95% confidence interval [CI]: 1.08, 1.66). SEV outperformed BEV in the postoperative mortality. There were no significant differences in the incidence postoperative stroke, proportion of pacemaker implantation, and the incidence of moderate-to-severe perivalvular leak between the SEV and BEV groups (P>0.05). Conclusion SEV is superior to BEV in all-cause mortality, but comparable in postoperative stroke, moderate-to-severe perivalvular leakage, pacemaker implantation and other postoperative complications.

Key words: transcatheter aortic valve replacement, self-expanding valves, balloon-expandable valves, complications

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