《世界卫生组织结核病操作手册模块6:结核病及其共患病》(第3版)解读

doi:10.3969/j.issn.1004-583X.2025.03.014

临床荟萃 ›› 2025, Vol. 40 ›› Issue (3): 270-274.doi: 10.3969/j.issn.1004-583X.2025.03.014

《世界卫生组织结核病操作手册模块6:结核病及其共患病》(第3版)解读

曾坚, 王小敏, 方木通, 卢水华()

深圳市第三人民医院/国家感染性疾病临床医学研究中心肺病一科, 广东深圳 518112

收稿日期:2025-03-10 出版日期:2025-03-20 发布日期:2025-03-25
通讯作者: 卢水华 E-mail:lushuihua66@126.com
基金资助:
深圳医学科学院深圳市医学研究专项基金——泛用性超短程方案治疗药物敏感性和耐药肺结核的多中心随机对照试验(C2405002);深圳市科技计划“揭榜挂帅”技术攻关项目——重大疾病新型生物标志物及检测技术的研发与应用(JSGGZD20220822095200001)

Interpretation for the third edition of WHO Operational Handbook on Tuberculosis, Module 6: Tuberculosis and Comorbidities

Zeng Jian, Wang Xiaomin, Fang Mutong, Lu Shuihua()

Pulmonary Department, Shenzhen Third People’s Hospital, National Clinical Research Center for Infectious Disease, Shenzhen 518112, China

Received:2025-03-10 Online:2025-03-20 Published:2025-03-25
Contact: Lu Shuihua E-mail:lushuihua66@126.com

摘要/Abstract

摘要：

结核病是全球重大公共卫生挑战,其与多种共患病(精神障碍、HIV感染及糖尿病)的相互作用显著影响患者预后。2025年1月,世界卫生组织发布的第3版《结核病操作手册模块6:结核病及其共患病》系统整合了结核病及其主要共病的管理策略。本文从精神障碍及物质使用障碍、HIV感染和糖尿病3个核心共病切入,解读操作手册的关键建议,涵盖筛查工具、综合治疗策略及预防措施,旨在为临床实践提供循证指导,优化结核病共病患者的全程管理。

关键词: 结核, 精神障碍, HIV, 糖尿病, 总结性报告

Abstract:

Tuberculosis (TB) is a major global public health challenge, and its interaction with a variety of comorbidities like mental disorder, HIV infection and diabetes significantly affects the prognosis of patients. In January 2025, the World Health Organization (WHO) released the third edition of the WHO Operational Handbook on Tuberculosis, Module 6: Tuberculosis and Comorbidities, which systematically integrated the management strategy of TB and comorbidities. Based on the three core comorbidities of mental and substance-use disorders, human immunodeficiency virus (HIV) infection and diabetes, this paper interprets the key recommendations for the operation manual including screening tools, comprehensive treatment approach, and preventive measures. it aims to provide evidence-based guidance for clinical practice and optimize the whole process management of TB patients.

Key words: tuberculosis, mental disorders, HIV, diabetes, consensus development conference

中图分类号:

曾坚, 王小敏, 方木通, 卢水华. 《世界卫生组织结核病操作手册模块6:结核病及其共患病》(第3版)解读[J]. 临床荟萃, 2025, 40(3): 270-274.

Zeng Jian, Wang Xiaomin, Fang Mutong, Lu Shuihua. Interpretation for the third edition of WHO Operational Handbook on Tuberculosis, Module 6: Tuberculosis and Comorbidities[J]. Clinical Focus, 2025, 40(3): 270-274.

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《世界卫生组织结核病操作手册模块6:结核病及其共患病》(第3版)解读

Interpretation for the third edition of WHO Operational Handbook on Tuberculosis, Module 6: Tuberculosis and Comorbidities

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