卵圆孔未闭:基于影像学证据的相关中枢神经机制

doi:10.3969/j.issn.1004-583X.2025.02.014

摘要/Abstract

摘要：

卵圆孔未闭是在青年人中发病率较高的一种先天性心脏缺陷,分流量较大时一般会引起神经系统症状,相关机制还不明确,目前主要有反常栓塞,皮质扩散抑制,血管活性因子等几种假说。介入封堵术是目前主要的治疗方法,大部分患者术后神经疾病症状有所减轻,随机对照试验为此提供了有力证明。本文总结了卵圆孔未闭相关的中枢神经机制,回顾了近来对于封堵术疗效的研究成果,收集了相关脑部结构及功能影像学的证据,并希望从脑功能修复方面评价封堵术的疗效,为临床诊断及治疗相关疾病提供新的理论依据。

关键词: 卵圆孔, 未闭, 神经机制, 封堵术, 影像学, 脑功能

中图分类号:

R541.1

崔凯歌, 刘丽莹, 孙利强, 胡婧, 于佳琪, 贾娟, 杨冀萍. 卵圆孔未闭:基于影像学证据的相关中枢神经机制[J]. 临床荟萃, 2025, 40(2): 172-179.

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参考文献 89

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卵圆孔未闭:基于影像学证据的相关中枢神经机制

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