CD163在常见肿瘤中的临床意义及研究进展

doi:10.3969/j.issn.1004-583X.2022.07.014

摘要/Abstract

摘要：

CD163属于清道夫受体家族,是人体血红蛋白-触珠蛋白清除剂的亲和力受体,也是M2型肿瘤相关巨噬细胞表面特异性标志物。CD163是一种双重免疫调节剂,能够刺激免疫反应,又可以促进肿瘤细胞的增殖、侵袭及转移,在机体中发挥着重要的作用。目前,多项研究发现CD163对乳腺癌、肺癌、胃癌、胰腺癌、结直肠癌、肝癌等肿瘤的发生发展有很大的影响,这也深受很多学者的关注。本文就CD163的结构功能及在常见肿瘤中的研究进展及临床意义展开综述。

关键词: CD163, 肿瘤, 乳腺癌, 肺癌, 胃癌, 胰腺癌, 结直肠癌, 肝癌

中图分类号:

R730.5

成红军, 潘志昂, 祝成楼, 马继春, 李伟东, 逯涛峰, 达明绪. CD163在常见肿瘤中的临床意义及研究进展[J]. 临床荟萃, 2022, 37(7): 653-657.

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https://lchc.magtechjournal.com/CN/Y2022/V37/I7/653

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CD163在常见肿瘤中的临床意义及研究进展

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