Interpretation for the third edition of WHO Operational Handbook on Tuberculosis, Module 6: Tuberculosis and Comorbidities

doi:10.3969/j.issn.1004-583X.2025.03.014

Abstract

Abstract:

Tuberculosis (TB) is a major global public health challenge, and its interaction with a variety of comorbidities like mental disorder, HIV infection and diabetes significantly affects the prognosis of patients. In January 2025, the World Health Organization (WHO) released the third edition of the WHO Operational Handbook on Tuberculosis, Module 6: Tuberculosis and Comorbidities, which systematically integrated the management strategy of TB and comorbidities. Based on the three core comorbidities of mental and substance-use disorders, human immunodeficiency virus (HIV) infection and diabetes, this paper interprets the key recommendations for the operation manual including screening tools, comprehensive treatment approach, and preventive measures. it aims to provide evidence-based guidance for clinical practice and optimize the whole process management of TB patients.

Key words: tuberculosis, mental disorders, HIV, diabetes, consensus development conference

CLC Number:

Zeng Jian, Wang Xiaomin, Fang Mutong, Lu Shuihua. Interpretation for the third edition of WHO Operational Handbook on Tuberculosis, Module 6: Tuberculosis and Comorbidities[J]. Clinical Focus, 2025, 40(3): 270-274.

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https://lchc.magtechjournal.com/EN/Y2025/V40/I3/270

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