Abstract: Rheumatoid arthritis is a chronic systemic autoimmune disease， which remains a difficult condition to manage due to unknown etiology. Reaching the standard control (treattotarget) is the main strategy of RA treatment. Longterm maintenance of remission is very important for the prevention of joint functional disability. The strategies and methods of target control include early treatment， combination therapy， targeted therapy， individualized treatment， chronotherapy and Chinese medicine treatment.

Key words: arthritis, rheumatoid, therapy