Clinical Focus >

2023 , Vol. 38 >Issue 1: 46 - 49

DOI: https://doi.org/10.3969/j.issn.1004-583X.2023.01.005

Correlation between coronary artery lesion and insulin resistance in patients with coronary heart disease combined with type 2 diabetes mellitus

  • Shangshi Zhang ,
  • Hongyan Zhu ,
  • Nan Li ,
  • Yingxi Chen
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  • a. Department of Cardiology,Shangrao People's Hospital,Shangrao 334000,China
    b. Department of Endocrinologyc,Shangrao People's Hospital,Shangrao 334000,China
    c. Department of Interventional Diagnosis and Treatment,Shangrao People's Hospital,Shangrao 334000,China

Received date: 2022-06-29

  Online published: 2023-03-03

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Abstract

Objective To investigate the correlation between the ischemic degree of coronary artery and calcification and insulin resistance in patients with coronary heart disease combined with type 2 diabetes mellitus (T2DM). Methods From January 1, 2020 to January 1, 2022, 80 patients with coronary heart disease combined with T2DM treated in the Shangrao People’s Hospital were recruited. According to the insulin resistance index in a homeostasis model (HOMA-IR), patients were divided into group A (HOMA-IR>2.69, n=42), and group B (HOMA-IR≤2.69, n=38).The length and arc of calcified vessels, number of coronary artery lesions, length of stent covering coronary arterylesions and Gensini score between the two groups were compared. The correlation between HOMA-IR and the above indicators was identified. Results Compared with those of group B, significantly longer length of calcified vessels and stent covering coronary artery lesions, larger arc of calcified vessels and number of coronary artery lesions, and higher Gensini scores were detected in group A (all P<0.05).Pearson correlation analysis showed that the length and arc of calcified vessels, number of coronary artery lesions, length of stent covering coronary arterylesions and Gensini scorewere positively correlated with HOMA-IR ( r=0.75, 0.51, 0.43, 0.38, and 0.59, respectively, all P<0.05). Conclusion There is a positive correlation between insulin resistance and coronary artery ischemia and calcification in patients with coronary heart disease combined with T2DM.

Key words： coronary disease; diabetes mellitus, type 2; coronary artery calcification; insulin resistance

Cite this article

Shangshi Zhang , Hongyan Zhu , Nan Li , Yingxi Chen . Correlation between coronary artery lesion and insulin resistance in patients with coronary heart disease combined with type 2 diabetes mellitus[J]. Clinical Focus, 2023 , 38(1) : 46 -49 . DOI: 10.3969/j.issn.1004-583X.2023.01.005

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