Abstract: It was believed that the symptoms and prognosis of patients with coronary heart disease(CHD) could be improved by beta receptor blockers (BBs). However, more and more evidencebased medical study suggests that the impact of BBs is declining in the treatment of patients with CHD. Clinical studies in recent years have shown that patients with CHD without myocardial infarction or heart failure (or cardiac dysfunction) do not benefit from BBs treatment. In addition to heart failure, there was no evidence to support the lifelong application of BBs in patients with CHD. And increasing the dose of BBs did not bring additional benefits to patients with CHD. Revascularization (PCI) treatment reduces the need for BBs in patients with CHD. In this paper, the status change of BBs in the treatment of CHD in recent years is reviewed.

Key words: beta receptor blockers, coronary disease, myocardial infarction, heart failure